| Title |
Cellular Cargo Delivery: Toward Assisted Fertilization by Sperm-Carrying Micromotors
|
|---|---|
| Published in |
Nano Letters, December 2015
|
| DOI | 10.1021/acs.nanolett.5b04221 |
| Pubmed ID | |
| Authors |
Mariana Medina-Sánchez, Lukas Schwarz, Anne K. Meyer, Franziska Hebenstreit, Oliver G. Schmidt |
| Abstract |
We present artificially motorized sperm cells-a novel type of hybrid micromotor, where customized microhelices serve as motors for transporting sperm cells with motion deficiencies to help them carry out their natural function. Our results indicate that metal-coated polymer microhelices are suitable for this task due to potent, controllable, and nonharmful 3D motion behavior. We manage to capture, transport, and release single immotile live sperm cells in fluidic channels that allow mimicking physiological conditions. Important steps toward fertilization are addressed by employing proper means of sperm selection and oocyte culturing. Despite the fact that there still remain some challenges on the way to achieve successful fertilization with artificially motorized sperms, we believe that the potential of this novel approach toward assisted reproduction can be already put into perspective with the present work. |
X Demographics
The data shown below were collected from the profiles of 2,015 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 255 | 13% |
| Japan | 68 | 3% |
| United Kingdom | 58 | 3% |
| Spain | 40 | 2% |
| India | 39 | 2% |
| Mexico | 37 | 2% |
| Germany | 35 | 2% |
| France | 31 | 2% |
| Canada | 26 | 1% |
| Other | 380 | 19% |
| Unknown | 1046 | 52% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1796 | 89% |
| Scientists | 146 | 7% |
| Practitioners (doctors, other healthcare professionals) | 48 | 2% |
| Science communicators (journalists, bloggers, editors) | 24 | 1% |
| Unknown | 1 | <1% |
Mendeley readers
The data shown below were compiled from readership statistics for 397 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | <1% |
| United States | 1 | <1% |
| United Kingdom | 1 | <1% |
| Unknown | 393 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 112 | 28% |
| Student > Master | 49 | 12% |
| Researcher | 48 | 12% |
| Student > Bachelor | 31 | 8% |
| Professor > Associate Professor | 14 | 4% |
| Other | 54 | 14% |
| Unknown | 89 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 101 | 25% |
| Physics and Astronomy | 46 | 12% |
| Chemistry | 36 | 9% |
| Materials Science | 35 | 9% |
| Biochemistry, Genetics and Molecular Biology | 26 | 7% |
| Other | 52 | 13% |
| Unknown | 101 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1882. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 March 2024.
All research outputs
#5,250
of 25,784,004 outputs
Outputs from Nano Letters
#1
of 14,612 outputs
Outputs of similar age
#38
of 398,793 outputs
Outputs of similar age from Nano Letters
#1
of 225 outputs
Altmetric has tracked 25,784,004 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,612 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 398,793 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 225 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.